Coordinator: Dr. Manuel Sánchez de la Torre
Chronic diseases considerably increase the number of deaths worldwide. Sleep apnea (OSA) is a chronic disease representing a major global health concern affecting approximately 10% of the middle-aged population. OSA is associated with increased cardiovascular and metabolic disease and overall mortality risks, and is nowadays considered a complex, heterogeneous and multi-component pathology. OSA heterogeneity has not been formally characterized, being this lack of identification one of the main challenges for its management. Additionally, there is an urgent need to further characterize the impact of OSA in high mortality and the social impact in diseases closely related with ageing. A better understanding of the impact of OSA will improve the diagnosis and management of these patients, reducing the cost associated to these diseases.
The overall objective of the present Project is to characterize the OSA phenotypes and to develop an innovative and cost-effective model for integral, precise and personalized care management of OSA using different levels of healthcare, telemedicine, smart technology, simplified diagnostic methods and “omics” tools.
Additionally, we aim to explore the impact of a chronic disease such as OSA in other diseases closely related with ageing and with high mortality and social impact, such as cognitive disorders (Alzheimer disease), cardiovascular disease and cancer.
Besides progress in disease knowledge, this CIBERES Project will contribute to innovations in:
These studies, done by a group of clinic and basic researches with a broad experience in this pathology and counting with experts in health-cost analysis, will have a direct impact in: