Pneumonia

Coordinator: Dr. Antoni Torres Martí

 

A new approach to understanding pneumonia: a copernican change.

  1. Due to the high consumption/use of antibiotics a high percentage of microorganisms have developed multiresistance, both in the community and, above all, in the hospital setting.
  2. There has been a dramatic increase in the number of immunosuppressed patients, who very often present pneumonia caused by different and difficult-to-treat microorganisms.
  3. “Classical” microorganisms such as Streptococcus pneumoniae, Legionella, Haemophilus, viruses and others are still frequent and represent a major burden.

Today, prevention is becoming a key health care strategy. In addition, a revolution in the field of microbiological diagnostic techniques is underway, with the implementation of rapid molecular methods that will make it possible to change the clinical management of pneumonia.

Lines of investigation

The  current pneumonia line at CIBERES proposes an investigational program in pneumonia based on these research lines:

  1. Multi drug resistant pathogens in the community and in the hospital;
  2. Microbial causes of pneumonia in immunosuppressed patients in the community and in the hospital;
  3. Microbial diagnosis focused on rapid molecular techniques;
  4. Streptococcus pneumoniae: genotyping, serotyping and resistances;
  5. Treatment of pneumonia focusing on new antibiotics, new forms of administration and coadjuvant therapies such as corticosteroids and immunoglobulins;
  6. Pneumonia prevention, focusing on nosocomial pneumonia in non-ventilated and ventilated patients;
  7. Animal models as a way to carry out trans-species and basic research in pneumonia;
  8. Other important pathogens in pneumonia such as Legionella, Haemophilus sp, Streptococcus pyogenes and Influenza virus.